Vingerhoets G, Jannes C, De Soete G, Van Nooten G
Department of Psychiatry and Neuropsychology, University Gent, Belgium.
J Clin Exp Neuropsychol. 1996 Apr;18(2):187-96. doi: 10.1080/01688639608408274.
One hundred and four patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) and a surgical control group undergoing major vascular or thoracic surgery (n = 18) were tested with the Auditory Verbal Learning Test (AVLT) at the following intervals: 1 day before, 1 week after, and 6 months after surgery. Early after surgery a significant decline in AVLT-performance was found, characterized by a smaller carry-over of learned words on subsequent acquisition trials. Six-month follow-up data revealed significant improvement in the delayed retention of words as compared to the preoperative assessment. No surgical group differences or time by group interaction effects were found. In the CPB group, deeper levels of hypothermia, reflecting longer and more extensive cardiac surgery, were associated with reduced improvement on retest.
104例接受体外循环心脏手术的患者以及18例接受大血管或胸科手术的手术对照组，在以下时间点接受听觉言语学习测试（AVLT）：手术前1天、手术后1周和手术后6个月。术后早期发现AVLT表现显著下降，其特征是在随后的习得试验中习得单词的迁移量较小。6个月的随访数据显示，与术前评估相比，单词的延迟记忆有显著改善。未发现手术组间差异或组间时间交互效应。在体外循环组中，反映心脏手术时间更长、范围更广的更低体温水平与复测时改善程度降低有关。
