Asato L, Wang M F, Chan Y C, Yeh S H, Chung H M, Chung S Y, Chida S, Uezato T, Suzuki I, Yamagata N, Kokubu T, Yamamoto S
Research Center of Comprehensive Medicine, University of the Ryukyus, Okinawa, Japan.
J Nutr Sci Vitaminol (Tokyo). 1996 Apr;42(2):87-96. doi: 10.3177/jnsv.42.87.
In a previous study we observed favorable effects of egg white on serum lipids in rats and mice. The present study was designed to elucidate these effects in 24 female university students with moderate hypercholesterolemia. About 30% of total protein was supplied with egg white, tofu or cheese. The experiment was conducted for a complete menstruation cycle of each subject. Lipid intake was about 30% of total energy intake. The energy intake of each subject was constant throughout the experiment. Body weight was measured every morning. Daily activity was measured by a pedometer. Blood was withdrawn after an overnight fast on the first, 15th and last days and serum lipids were measured. Body weight was measured every morning. Daily activity was measured by a pedometer. Blood was withdrawn after an overnight fast on the first, 15th and last days and serum lipids were measured. Body weight and daily activity were maintained in all the groups throughout the experiment. The egg white group showed a similar decrease in the total cholesterol (Total-C) concentration but a greater increase of high-density lipoprotein cholesterol (HDL-C) concentration as compared to the tofu group and a greater decrease in Total-C and low-density lipoprotein cholesterol (LDL-C) concentrations and a greater increase in the HDL-C concentration as compared to the cheese group (p < 0.05). The results indicate the favorable effects of egg white in the control of hypercholesterolemia.
在之前的一项研究中，我们观察到蛋清对大鼠和小鼠的血脂有有益影响。本研究旨在阐明这些影响在24名患有中度高胆固醇血症的女大学生中的情况。约30%的总蛋白由蛋清、豆腐或奶酪提供。实验针对每个受试者的一个完整月经周期进行。脂肪摄入量约占总能量摄入量的30%。在整个实验过程中，每个受试者的能量摄入量保持恒定。每天早晨测量体重。通过计步器测量日常活动量。在第1天、第15天和最后一天禁食过夜后采血并测量血脂。每天早晨测量体重。通过计步器测量日常活动量。在第1天、第15天和最后一天禁食过夜后采血并测量血脂。在整个实验过程中，所有组的体重和日常活动量均保持稳定。与豆腐组相比，蛋清组的总胆固醇（Total-C）浓度下降幅度相似，但高密度脂蛋白胆固醇（HDL-C）浓度升高幅度更大；与奶酪组相比，蛋清组的Total-C和低密度脂蛋白胆固醇（LDL-C）浓度下降幅度更大，HDL-C浓度升高幅度更大（p<0.05）。结果表明蛋清在控制高胆固醇血症方面具有有益作用。
