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腹腔镜与开腹阑尾切除术治疗急性阑尾炎的前瞻性研究

Laparoscopic compared with open appendicectomy for acute appendicitis: a prospective study.

作者信息

Chiarugi M, Buccianti P, Celona G, Decanini L, Martino M C, Goletti O, Cavina E

机构信息

University of Pisa Medical School, Department of Surgery, Italy.

出版信息

Eur J Surg. 1996 May;162(5):385-90.

PMID:8781920
Abstract

OBJECTIVE

To assess the benefits of laparoscopic appendicectomy over open appendicectomy and to evaluate the impact of the severity of appendicitis and of peritonitis on the advantages of the laparoscopic approach.

DESIGN

Prospective unrandomised study.

SETTING

University hospital, Italy.

SUBJECTS

137 consecutive patients with acute appendicitis, 60 of whom were treated by open and 77 by laparoscopic appendicectomy. Patients were subdivided according to the severity of appendicitis and the presence of peritonitis.

MAIN OUTCOME MEASURES

Duration of operation, consumption of analgesics, duration of hospital stay, overall complications, wound infection.

RESULTS

Hospital stay (median 2.5 days, range 1-18 compared with 4, range 2-22 p < 0.0001). and wound infection (3/77 (4%) compared with 13/60 (22%), p 0.02) were significantly lower after laparoscopic operation. The incidence of wound infection was significantly lower when subgroups were analysed separately.

CONCLUSIONS

Hospital stay and wound infection rates were significantly lower after laparoscopic appendicectomy. With the exception of the wound infection rate, the variables studied may differ depending on the severity of the appendicitis and the presence of peritonitis. Result of comparative studies should be carefully interpreted when the two groups are not stratified for these features.

摘要

目的

评估腹腔镜阑尾切除术相对于开腹阑尾切除术的益处,并评估阑尾炎严重程度和腹膜炎对腹腔镜手术优势的影响。

设计

前瞻性非随机研究。

地点

意大利大学医院。

研究对象

137例连续性急性阑尾炎患者,其中60例行开腹阑尾切除术,77例行腹腔镜阑尾切除术。根据阑尾炎的严重程度和腹膜炎的存在情况对患者进行细分。

主要观察指标

手术时间、镇痛药用量、住院时间、总体并发症、伤口感染。

结果

腹腔镜手术后住院时间(中位数2.5天,范围1 - 18天,相比之下开腹手术为4天,范围2 - 22天,p < 0.0001)和伤口感染率(77例中有3例(4%),相比之下开腹手术60例中有13例(22%),p = 0.02)显著更低。分别分析亚组时,伤口感染发生率显著更低。

结论

腹腔镜阑尾切除术后住院时间和伤口感染率显著更低。除伤口感染率外,所研究的变量可能因阑尾炎的严重程度和腹膜炎的存在情况而有所不同。当两组未针对这些特征进行分层时,对比较研究的结果应谨慎解读。

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