温度对局部局部麻醉所致不适的影响。
The effect of temperature on the discomfort caused by topical local anaesthesia.
作者信息
Callear A B
机构信息
Birmingham and Midland Eye Hospital, Birmingham, England.
出版信息
J R Soc Med. 1995 Dec;88(12):709p-11p. doi: 10.1177/014107689508801221.
The warming of local anaesthetic solutions to reduce the pain felt on injection is common practice in a number of medical sub-specialties. A study was undertaken to assess the effect of temperature on the discomfort caused by local anaesthetic eye drops. Tropical anaesthetics amethocaine 1%, oxybuprocaine 0.4% and lignocaine 4% were studied, and after the application of strict exclusion criteria 60 patients were selected, 20 patients for each anaesthetic. Each patient group received a topical anaesthetic at 42 degrees C in one eye and at room temperature in the other. A 10 point visual analogue scale was used to assess the discomfort experienced. No statistically significant difference was found between the discomfort caused by drops at each temperature for any of the three anaesthetics studied. There appears no benefit in warming topical anaesthetic agents prior to their use.
在许多医学亚专业中，将局部麻醉溶液加温以减轻注射时的疼痛是一种常见做法。一项研究旨在评估温度对局部麻醉眼药水所致不适的影响。研究了1%的丁卡因、0.4%的奥布卡因和4%的利多卡因这几种局部麻醉药，在应用严格的排除标准后，选取了60例患者，每种麻醉药20例患者。每个患者组一只眼睛滴入42摄氏度的局部麻醉药，另一只眼睛滴入室温的局部麻醉药。使用10分视觉模拟量表评估所经历的不适。在所研究的三种麻醉药中，任何一种在每个温度下滴入眼药水所致的不适之间均未发现统计学上的显著差异。在使用前加温局部麻醉剂似乎并无益处。
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