Bell R W, Butt Z A, Gardner R F
Princess Alexandra Eye Pavilion, Royal Infirmary of Edinburgh, UK.
Eye (Lond). 1996;10 ( Pt 5):558-60. doi: 10.1038/eye.1996.129.
The injection of local anaesthetic solutions is frequently a painful and unpleasant experience for patients. A double-masked randomised controlled trial was performed to study the potential benefit of warming lignocaine during local anaesthetic minor surgical procedures on the eyelids. The pain of subcutaneous injection of 1.5 ml of 2% lignocaine at room temperature (cold) and body temperature (warm) was compared in 60 patients during the surgical incision of solitary meibomian cysts of one eyelid. Patients were randomly allocated to receive either warm or cold lignocaine. Pain was assessed subjectively by the use of a linear analogue pain scale ranging from 0 to 100. The median pain score for the group receiving cold anaesthetic (19.5) was found to be greater than that for the warm group (10.0; p = 0.02). In conclusion, the simple process of warming lignocaine to 37 degrees C was found to reduce the pain associated with its injection significantly. It is recommended that this technique be more widely adopted in order to minimise patients' discomfort.
对患者而言，注射局部麻醉剂溶液常常是一种痛苦且不愉快的经历。开展了一项双盲随机对照试验，以研究在眼睑局部麻醉小手术过程中加热利多卡因的潜在益处。在对60例单发性睑板腺囊肿进行手术切开时，比较了在室温（冷）和体温（热）下皮下注射1.5毫升2%利多卡因的疼痛程度。患者被随机分配接受热或冷的利多卡因。使用范围为0至100的线性模拟疼痛量表对疼痛进行主观评估。结果发现，接受冷麻醉组的中位疼痛评分（19.5）高于热麻醉组（10.0；p = 0.02）。总之，发现将利多卡因加热至37摄氏度这一简单过程可显著减轻注射相关的疼痛。建议更广泛地采用该技术，以尽量减少患者的不适。
