el-Newihi H M, Dellinger G W, Mihas A A, Achord J L
Division of Digestive Diseases, Veterans Affairs Medical Center, Jackson, MS, USA.
South Med J. 1996 Sep;89(9):906-10. doi: 10.1097/00007611-199609000-00013.
An elderly black man was admitted to our institution with macrocytic anemia, dysphagia, and significant weight loss. Results of an esophagogram were suggestive of achalasia. Gastric adenocarcinoma infiltrating the gastric cardia was seen on gastroscopy. The mode of presentation of gastric cancer in this case has not been previously reported in association with pernicious anemia. Patients with pernicious anemia are at higher risk of having gastrointestinal neoplasms than is the general population. We review the current literature and address the controversy concerning the need to subject patients with pernicious anemia to surveillance with upper gastrointestinal endoscopy.
一位老年黑人男性因大细胞性贫血、吞咽困难和显著体重减轻入住我院。食管造影结果提示贲门失弛缓症。胃镜检查发现胃腺癌浸润胃贲门。这种情况下胃癌的表现方式此前尚未见与恶性贫血相关的报道。恶性贫血患者发生胃肠道肿瘤的风险高于普通人群。我们回顾了当前的文献，并探讨了关于恶性贫血患者是否需要接受上消化道内镜监测的争议。
