Macdonald P M, Smibert C A
Department of Biological Sciences, Stanford University, Stanford, California 94305-5020, USA.
Curr Opin Genet Dev. 1996 Aug;6(4):403-7. doi: 10.1016/s0959-437x(96)80060-8.
Translational regulation of maternal mRNAs serves to constrain their activities in both time and space. Both types of constraint might be expected to be critical for normal development and the rather short list of maternal mRNAs for which this has been shown to be true has expanded considerably over the past year. Substantial progress has also been reported in the identification and characterization of the cis-acting elements and trans-acting factors that mediate translational regulation and their interactions with one another.
母源mRNA的翻译调控有助于在时间和空间上限制其活性。这两种限制对于正常发育可能都至关重要，在过去一年里，已被证明确实如此的母源mRNA清单虽短但大幅增加。在介导翻译调控的顺式作用元件和反式作用因子的鉴定与表征以及它们之间的相互作用方面也报道了重大进展。
