Honig S, Gorevic P, Hoffstein S, Weissmann G
Am J Med. 1977 Jul;63(1):161-4. doi: 10.1016/0002-9343(77)90128-0.
The diagnosis of gout and pseudogout has traditionally been established by the identification, in synovial fluid, of monosodium urate and calcium pyrophosphate dihydrate crystals with compensated polarizing light microscopy. In this paper the utility of electron microscopy in establishing these diagnosis in two cases, when the conventional means of synovial fluid analysis had failed to do so, is discussed. The application of ultrastructural analysis of synovial fluid increases diagnostic capability in the crystal deposition diseases, and it is recommended for those patients in whom the more usual studies have not established a diagnosis.
痛风和假性痛风的诊断传统上是通过在滑液中利用补偿偏振光显微镜识别尿酸钠和二水焦磷酸钙晶体来确立的。本文讨论了在两例常规滑液分析未能确诊的情况下，电子显微镜在确立这些诊断中的作用。滑液超微结构分析的应用提高了晶体沉积疾病的诊断能力，对于那些常规检查未能确诊的患者推荐使用。
