Smart R C, Barbagallo S, Slater G L, Kuo R S, Butler S P, Drummond R P, Sekel R
Department of Nuclear Medicine, St. George Hospital, Kogarah, NSW, Australia.
J Arthroplasty. 1996 Jun;11(4):445-52. doi: 10.1016/s0883-5403(96)80035-0.
To define the precision (reproducibility) of measurement of periprosthetic bone mineral density and bone mineral content, dual-energy x-ray absorptiometry scans were obtained on 45 randomly selected patients who had had a unilateral total hip arthroplasty within the previous 3 years. The coefficients of variation of the bone mineral density in the proximal Gruen zones were 5.0 and 5.3%, corresponding to errors of 0.07 and 0.11 g/cm2. The coefficients of variation of the bone mineral density for the distal zones averaged 2.8%, with an error of 0.08 g/cm2. The coefficients of variation of the bone mineral content were 4.8 and 2.9% for the proximal and distal zones. The contralateral femur was also scanned in 32 of the patients. For the contralateral femur bone mineral density, the coefficients of variation were 5.0% for the proximal zones and 4.8% for the distal zones. The bone mineral content was 6.0% for the contralateral regions. These results imply that differences in bone mineral density greater than 0.16 g/cm2 (2 standard errors) can be reliably measured. Dual-energy x-ray absorptiometry therefore provides a highly reproducible technique for quantitatively monitoring the changes in bone density that occur after total hip arthroplasty.
为了确定假体周围骨矿物质密度和骨矿物质含量测量的精度（可重复性），对45例在过去3年内接受单侧全髋关节置换术的随机选择患者进行了双能X线吸收测定扫描。近端Gruen区骨矿物质密度的变异系数分别为5.0%和5.3%，对应误差为0.07和0.11g/cm²。远端区骨矿物质密度的变异系数平均为2.8%，误差为0.08g/cm²。近端和远端区骨矿物质含量的变异系数分别为4.8%和2.9%。32例患者还对侧股骨进行了扫描。对于对侧股骨骨矿物质密度，近端区变异系数为5.0%，远端区为4.8%。对侧区域骨矿物质含量为6.0%。这些结果表明，骨矿物质密度差异大于0.16g/cm²（2个标准误差）可以可靠测量。因此，双能X线吸收测定法为定量监测全髋关节置换术后发生的骨密度变化提供了一种高度可重复的技术。
