Larsen E B, Gerlach J
Psychiatry Department P, St Hans Hospital, Roskilde, Denmark.
Acta Psychiatr Scand. 1996 May;93(5):381-8. doi: 10.1111/j.1600-0447.1996.tb10664.x.
Attitude towards treatment, side-effects, mental state and quality of life was assessed in 53 chronic schizophrenic out-patients on maintenance treatment with depot neuroleptics. It was found that 60% of the patients viewed depot medication positively, while only 8% viewed it negatively. Only 70% of patients complained about side-effects, even though 94% had scored as having them. Hypokinesia and hyperkinesis were the side-effects least noticed by the patients, but most noticed by the treating physician, while the opposite was the case with psychic side-effects. Only 49% of patients thought they had a psychotic illness, and there was no correlation between the patients' own evaluation of the severity of their illness and their score on the Positive and Negative Symptom Scale (PANSS) or the treating physician's evaluation. Quality of life did not correlate with either side-effect score or PANSS score. The schizophrenic patients' assessment of their condition was therefore in general different both from that of the treating physician and from that determined using rating scales.
对53名使用长效抗精神病药物进行维持治疗的慢性精神分裂症门诊患者的治疗态度、副作用、精神状态和生活质量进行了评估。结果发现，60%的患者对长效药物持积极看法，而只有8%的患者持消极看法。尽管94%的患者有副作用评分，但只有70%的患者抱怨有副作用。运动减少和运动增多是患者最不易察觉但治疗医生最易察觉的副作用，而精神副作用则相反。只有49%的患者认为自己患有精神病，患者自身对疾病严重程度的评估与他们在阳性和阴性症状量表（PANSS）上的得分或治疗医生的评估之间没有相关性。生活质量与副作用评分或PANSS评分均无相关性。因此，精神分裂症患者对自身状况的评估总体上与治疗医生的评估以及使用评定量表得出的评估均不同。
