Fortoul T I, Osorio L S, Tovar A T, Salazar D, Castilla M E, Olaiz-Fernández G
Departamento de Biologia Celular y Tisular, Facultad de Medicina, UNAM, Mexico City, Mexico.
Environ Health Perspect. 1996 Jun;104(6):630-2. doi: 10.1289/ehp.96104630.
In autopsies performed on residents of Mexico City during the 1950s and 1980s (45 males and 24 females and 42 males and 42 females, respectively), concentrations of cadmium, copper, cobalt, nickel, and lead in the lungs were studied by atomic absorption spectrometry. Sharp increases were noted in samples taken in the 1980s compared to those from the 1950s. In samples from both time periods, the concentrations were influenced by gender. Smoking was not associated with higher levels of the metals. Only lead seemed to have a relation with age. The enormous differences by gender in the 1950s could be due to different patterns of exposure. The differences among samples from both periods appear to be associated with the increase of air pollutants in the metropolitan areas of Mexico City during the years under study. These results reinforce the importance of studying lung tissue to monitor air pollution by metals.
在20世纪50年代和80年代对墨西哥城居民进行的尸检中(分别为45名男性和24名女性以及42名男性和42名女性),通过原子吸收光谱法研究了肺中镉、铜、钴、镍和铅的浓度。与20世纪50年代的样本相比,20世纪80年代采集的样本中这些金属的浓度显著增加。在两个时期的样本中,浓度都受到性别的影响。吸烟与这些金属的较高含量无关。只有铅似乎与年龄有关。20世纪50年代性别间的巨大差异可能是由于不同的接触模式。两个时期样本之间的差异似乎与所研究年份墨西哥城大都市区空气污染物的增加有关。这些结果强化了通过研究肺组织来监测金属空气污染的重要性。