Giménez Martín E, Martín Mateo M C
Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias, Universidad de Valladolid.
Rev Esp Oncol. 1985;32(4):633-40.
In cancer process there have been found metabolic changes in several elements, especially in respect to copper. It has been proved that there is an alteration in the serum levels of some metals, and in their distribution in the proteins binding them. On the other hand, there exist, also, ceruloplasmin differences between patients serum and the control. Our work has been carried out to study the trace element metabolism in lung cancer, as well as chromium and zinc contents. Electrophoretic techniques have been applied to study the protein levels.
在癌症进程中,已发现多种元素存在代谢变化,尤其是铜。已证实某些金属的血清水平及其在结合它们的蛋白质中的分布发生了改变。另一方面,患者血清与对照组之间也存在铜蓝蛋白差异。我们开展这项工作是为了研究肺癌中的微量元素代谢以及铬和锌的含量。已应用电泳技术来研究蛋白质水平。