Groeneveld F P, Bareman F P, Barentsen R, Dokter H J, Drogendijk A C, Hoes A W
Department of General Practice, Erasmus University of Rotterdam, The Netherlands.
Maturitas. 1996 Apr;23(3):293-9. doi: 10.1016/0378-5122(95)00989-2.
To determine more closely the relationship between vasomotor symptoms, well-being and climacteric status according to the last menstrual bleeding and according to the women themselves.
A population-based cross-sectional study was executed using a postal questionnaire. Well-being of women with and without vasomotor symptoms was compared, for the different menopausal statuses. All 2729 women living in a commuter suburb of Rotterdam aged 45-60 years were approached of whom 1947 (71.3%) responded. Well-being was measured by the Inventory of Subjective Health (ISH) and three subscales of the Sickness Impact Profile (SIP).
The results showed that the relationship between vasomotor symptoms and well-being was dependent on climacteric status. Pre- and (middle and late) postmenopausal women with vasomotor symptoms more often experienced a relatively lower level of well-being compared to women without these symptoms. However, when the prevalence of vasomotor symptoms is as its peak, i.e. in late perimenopause, a difference in the level of well-being between women with and without vasomotor symptoms was absent.
It is concluded that well-being and vasomotor symptoms were inversely related in all menopausal statuses except for the (late) perimenopausal phase. For this no somatic explanation seems plausible. A more social scientific explanation is suggested.
根据末次月经出血情况以及女性自身情况，更深入地确定血管舒缩症状、幸福感与更年期状态之间的关系。
采用邮寄问卷的方式进行基于人群的横断面研究。比较了不同绝经状态下有和没有血管舒缩症状的女性的幸福感。研究对象为居住在鹿特丹通勤郊区的所有2729名45 - 60岁女性，其中1947名（71.3%）做出了回应。幸福感通过主观健康量表（ISH）和疾病影响量表（SIP）的三个子量表进行测量。
结果表明，血管舒缩症状与幸福感之间的关系取决于更年期状态。与没有这些症状的女性相比，有血管舒缩症状的绝经前及（绝经中和绝经后）女性更常经历相对较低水平的幸福感。然而，当血管舒缩症状的患病率达到峰值时，即在围绝经期晚期，有和没有血管舒缩症状的女性在幸福感水平上没有差异。
得出的结论是，除了（晚期）围绝经期阶段外，在所有绝经状态下，幸福感与血管舒缩症状呈负相关。对此，似乎没有合理的躯体解释。建议从社会科学角度进行更多解释。
