Honer W G, Kopala L C, Locke J J, Lapointe J S
Department of Psychiatry, University of British Columbia, Jack Bell Research Centre, Vancouver, Canada.
Schizophr Res. 1996 May;20(1-2):231-4. doi: 10.1016/0920-9964(95)00105-0.
A previous report of cerebral hemiatrophy and schizophrenia added to the list of neurodevelopmental abnormalities associated with schizophrenia. In a new case, the birth history indicated perinatal hemorrhage and prematurity (30-31 weeks of gestation). CT and MR imaging showed reduction in left hemisphere size with ventricular enlargement and mild skull thickening. Loss of periventricular white matter was detected. Changes in skull thickness, size of air cells and volume of the cranial vault may be measurable correlates of putative developmental abnormalities in schizophrenia.
先前一份关于脑半球萎缩与精神分裂症的报告，为与精神分裂症相关的神经发育异常清单增添了内容。在一个新病例中，出生史显示存在围产期出血和早产（妊娠30 - 31周）。CT和磁共振成像显示左半球体积减小，伴有脑室扩大和颅骨轻度增厚。检测到脑室周围白质丢失。颅骨厚度、气房大小和颅腔容积的变化可能是精神分裂症假定发育异常的可测量相关指标。
