Hantson P, Benaissa M, Clemessy J L, Baud F J
Réanimation Toxicologique, Hôpital Fernand Widal, Paris, France.
Intensive Care Med. 1996 May;22(5):453-5. doi: 10.1007/BF01712165.
We observed a 51-year-old woman who was admitted for severe amitriptyline overdose. Besides major cardiovascular complications, the patient developed severe hyperpyrexia with a central body temperature of more than 43 degrees C for 5 h. The patient died on day 3 from cardiocirculatory collapse and arrhythmias. Hyperthermia was unresponsive to cooling with ice water, gastric lavage, muscle relaxation, and dantrolene and bromocriptine administration. The possible mechanisms of refractory hyperthermia are discussed.
我们观察了一名因阿米替林严重过量而入院的51岁女性。除了主要的心血管并发症外，该患者还出现了严重高热，中心体温超过43摄氏度达5小时。患者在第3天死于心循环衰竭和心律失常。用冰水降温、洗胃、肌肉松弛以及给予丹曲林和溴隐亭均无法缓解高热。本文讨论了难治性高热的可能机制。
