Ween J E, Verfaellie M, Alexander M P
Rehabilitation Hospital of Rhode Island, N. Smithfield, USA.
Neurology. 1996 Sep;47(3):795-801. doi: 10.1212/wnl.47.3.795.
Verbal material may be processed by semantic and phonologic systems. Damage to these language systems may also impair memory. We classified 16 mildly aphasic patients according to phonologic and lexicosemantic abilities, tested them on a variety of short- and long-term memory measures, and correlated behavioral deficits with lesion location. Aphasia impaired both short- and long-term memory. Phonologic impairment affected only digit span performance. Lexicosemantic deficits impaired self-organized encoding of word lists. Memory impairment was not associated with specific lesion locations. Persistent verbal-memory impairments accompanying even mild residual aphasia may be responsible for much of the difficulty mildly aphasic patients experience returning to vocational, academic, and social life. Co-occurrence of these deficits probably reflects their underlying dependence on similar processing systems.
言语材料可能由语义和语音系统进行处理。这些语言系统受损也可能损害记忆。我们根据语音和词汇语义能力对16名轻度失语症患者进行了分类,对他们进行了各种短期和长期记忆测试,并将行为缺陷与病变位置进行了关联。失语症损害了短期和长期记忆。语音障碍仅影响数字广度表现。词汇语义缺陷损害了单词列表的自组织编码。记忆障碍与特定的病变位置无关。即使是轻度残留失语症伴随的持续性言语记忆障碍,可能是轻度失语症患者在回归职业、学术和社会生活中遇到诸多困难的原因。这些缺陷的同时出现可能反映了它们对相似处理系统的潜在依赖。