Department of Psychology, University of Crete, Greece.
Neuropsychologia. 2013 Aug;51(9):1773-6. doi: 10.1016/j.neuropsychologia.2013.06.003. Epub 2013 Jun 11.
While memory deficits in aphasia have been reported in several studies, it has been suggested that these deficits are not due to the presence of aphasia, but rather to the left hemisphere lesion per se. In order to investigate this hypothesis, we tested 64 aphasic and 15 non-aphasic patients with left brain damage on verbal and visuospatial span tasks. Analyses revealed lower than expected performance on all four primary memory tasks for the aphasic, but not for the non-aphasic group. Moreover, comparison of the three lesion-location groups (posterior, anterior, and global) did not reveal statistically significant differences. The present data show that aphasic patients demonstrate memory deficits, which are not specific to the verbal modality, and contradict the notion that primary memory impairment is not due to the presence of aphasia, but rather to a lesion in the left hemisphere per se. Overall our study suggests that verbal and visuospatial, primary memory deficits in patients with left hemisphere lesions are possibly dependent on the presence of aphasia, but not on lesion location or lesion size.
尽管在几项研究中报告了失语症患者的记忆缺陷，但有人认为这些缺陷不是由于失语症的存在，而是由于左半球损伤本身。为了验证这一假设，我们对 64 名左脑损伤的失语症患者和 15 名非失语症患者进行了言语和视空间跨度任务的测试。分析显示，失语症组在所有四项主要记忆任务中的表现均低于预期，但非失语症组则不然。此外，对三个损伤部位组（后部、前部和整体）的比较并未显示出统计学上的显著差异。本研究数据表明，失语症患者表现出记忆缺陷，这些缺陷不仅限于言语模式，这与主要记忆障碍不是由于失语症的存在，而是由于左半球损伤本身的观点相矛盾。总的来说，我们的研究表明，左半球损伤患者的言语和视空间主要记忆缺陷可能依赖于失语症的存在，而不依赖于损伤部位或损伤大小。
