厌氧环境对葡萄球菌抗菌药敏性的影响
Effect of anaerobiosis on antimicrobial susceptibility of staphylococci.
作者信息
Harrell L J, Evans J B
出版信息
Antimicrob Agents Chemother. 1977 Jun;11(6):1077-8. doi: 10.1128/AAC.11.6.1077.
Abstract
The minimum inhibitory concentration (MIC) of 12 antibiotics was determined for four strains of staphylococci (representing the three major species) under aerobic and anaerobic conditions by using the broth dilution method. Nine of the antibiotics showed no significant difference between aerobic and anaerobic MIC for any of the four cultures. Gentamicin and kanamycin showed a small, but significant, increase in MIC for at least two strains under anaerobic conditions. Trimethoprim was less effective against all strains under anaerobic conditions.
摘要
采用肉汤稀释法，在需氧和厌氧条件下测定了12种抗生素对4株葡萄球菌（代表三个主要菌种）的最低抑菌浓度（MIC）。对于这四种培养物中的任何一种，9种抗生素的需氧和厌氧MIC之间均无显著差异。庆大霉素和卡那霉素在厌氧条件下，对至少两株菌株的MIC有小幅但显著的升高。甲氧苄啶在厌氧条件下对所有菌株的效果均较差。
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