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使用自膨式镍钛诺施特雷克支架对肿瘤性狭窄进行姑息治疗。

Palliative treatment of neoplastic strictures by self-expanding nitinol Strecker stent.

作者信息

Pocek M, Maspes F, Masala S, Squillaci E, Assegnati G, Moraldi A, Simonetti G

机构信息

Department of Radiology, University of Rome Tor Vergata, Italy.

出版信息

Eur Radiol. 1996;6(2):230-5. doi: 10.1007/BF00181157.

DOI:10.1007/BF00181157
PMID:8797986
Abstract

The purpose of this study was to evaluate technical and clinical results of self-expanding esophageal stent implanted in patients with malignant esophageal strictures and clinically significant dysphagia. From June 1992 to September 1994, 27 patients with inoperable tumors of the esophagus or gastric cardiac were treated by placement of 37 self-expanding nitinol stents. Water-soluble contrast and endoscopy studies were performed after the procedure and during the follow-up period. Successful stenting of the stricture was achieved in 27 patients. The mean dysphagia grade dropped from 2.3 to 1 (SD +/- 0.54) immediately after the procedure. After the insertion of the stent, 16 patients died in a period of time ranging from 0 to 13 months (mean 5.6 months), whereas at the end of the study 11 patients were alive 4-15 months after the procedure (mean 8.3 months). No major complications were observed. The results of this study are encouraging because esophageal stent placement was technically easy and clinically effective.

摘要

本研究的目的是评估自膨式食管支架植入恶性食管狭窄且有明显吞咽困难患者的技术和临床效果。1992年6月至1994年9月,27例无法手术的食管癌或贲门癌患者接受了37枚自膨式镍钛合金支架植入治疗。术后及随访期间进行了水溶性造影和内镜检查。27例患者的狭窄部位成功置入支架。术后吞咽困难平均分级立即从2.3降至1(标准差±0.54)。支架置入后,16例患者在0至13个月(平均5.6个月)内死亡,而在研究结束时,11例患者在术后4至15个月(平均8.3个月)仍存活。未观察到重大并发症。本研究结果令人鼓舞,因为食管支架置入技术操作简便且临床效果显著。

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本文引用的文献

1
Malignant esophageal strictures: treatment with a self-expanding nitinol stent.恶性食管狭窄:使用自膨式镍钛合金支架治疗。
Radiology. 1993 Jun;187(3):661-5. doi: 10.1148/radiology.187.3.7684528.
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[Palliative treatment of esophageal neoplastic stenoses with self-expanding metallic stents].
Radiol Med. 1993 Nov;86(5):647-56.
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The insertion of oesophagogastric tubes in malignant oesophageal strictures: endoscopy or surgery?
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Expandable tubular stents for treatment of arterial occlusive diseases: experimental and clinical results. Work in progress.用于治疗动脉闭塞性疾病的可扩张管状支架:实验与临床结果。研究进展中。
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[Adenocarcinoma of the distal esophagus treated with external and intracavitary radiotherapy. Description of a clinical case and review of the literature].[远端食管癌的外照射与腔内放疗治疗。1例临床病例描述及文献综述]
Minerva Gastroenterol Dietol. 1991 Jul-Sep;37(3):187-93.
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Palliative treatment of esophageal carcinoma using esophageal dilation and prosthesis.使用食管扩张术和假体对食管癌进行姑息治疗。
Gastroenterol Clin North Am. 1991 Dec;20(4):717-29.
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A prospective comparison of laser therapy and intubation in endoscopic palliation for malignant dysphagia.
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Endoscopic Nd-YAG laser therapy as palliative treatment for esophageal and cardial cancer. Parameters affecting long-term outcome.内镜下钕钇铝石榴石激光治疗作为食管癌和贲门癌的姑息治疗。影响长期疗效的参数。
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