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检测膀胱输尿管反流和肾瘢痕形成时针对Tamm-Horsfall蛋白的自身抗体。

Autoantibodies to Tamm-Horsfall protein in detection of vesicoureteric reflux and kidney scarring.

作者信息

Fasth A, Hanson L A, Asscher A W

出版信息

Arch Dis Child. 1977 Jul;52(7):560-2. doi: 10.1136/adc.52.7.560.

Abstract

Measurement of IgG antibodies to Tamm-Horsfall protein (ATHA) in 92 bacteriuric schoolgirls aged 5-12 did not show a significant rise compared with the titres found in the sera of 24 healthy controls. ATHA titres showed no correlation with the presence of vesicoureteric reflux or kidney scarring and it is concluded that measurement of serum ATHA is of no value as a screening procedure for the detection of vesicoureteric reflux.

摘要

对92名年龄在5至12岁的患菌尿症女学生进行了抗Tamm-Horsfall蛋白IgG抗体(ATHA)检测,与24名健康对照者血清中的抗体滴度相比,未发现有显著升高。ATHA滴度与膀胱输尿管反流或肾瘢痕形成的存在无关,得出的结论是,检测血清ATHA作为筛查膀胱输尿管反流的方法没有价值。

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本文引用的文献

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Intrarenal reflux and the scarred kidney.肾内反流与瘢痕肾
Arch Dis Child. 1974 Jul;49(7):531-9. doi: 10.1136/adc.49.7.531.
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Host-parasite relationships in urinary tract infections.
J Infect Dis. 1973 Jun;127(6):726-30. doi: 10.1093/infdis/127.6.726.
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Urinary tract in schoolgirls with covert bacteriuria.隐匿性菌尿症女学生的尿路情况
Arch Dis Child. 1975 Apr;50(4):253-8. doi: 10.1136/adc.50.4.253.
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Editorial: Urinary tract infection: Value of early diagnosis.
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