Fasth A, Kollberg H
Acta Paediatr Scand. 1980 Mar;69(2):189-92. doi: 10.1111/j.1651-2227.1980.tb07058.x.
Sera from 35 patients, 17 boys and 18 girls, with cystic fibrosis were analysed for autoantibodies to the Tamm-Horsfall protein. Significantly (p less than 0.001) elevated levels of specific IgG and IgA, but not IgM antibodies to Tamm-Horsfall protein were found. There was a considerable overlap between the values in the disease group and the control group. The highest values were found among the patients with liver involvement. The patients with marked lung abnormalities as well as those with positive bacterial culture of sputum had normal antibody levels.
对35例囊性纤维化患者（17名男孩和18名女孩）的血清进行分析，检测其针对Tamm-Horsfall蛋白的自身抗体。结果发现，针对Tamm-Horsfall蛋白的特异性IgG和IgA水平显著升高（p<0.001），但IgM抗体水平未升高。疾病组和对照组的值有相当大的重叠。在有肝脏受累的患者中发现了最高值。肺部有明显异常的患者以及痰细菌培养呈阳性的患者抗体水平正常。
