Salimpour R
Arch Dis Child. 1977 Jul;52(7):587-9. doi: 10.1136/adc.52.7.587.
Of 125 newborn infants with tetanus studied clinically, 75 died. Hypothermia and bronchopneumonia were the commonest events leading to death. A sudden drop in the amount of sedation required, loss of or diminished tetanal signs, and hypothermia usually indicated the onset of bronchopneumonia. A later series of 108 cases with 75 deaths (54 necropsies) formed the basis of a pathological study. Pulmonary pathology was found in 46 out of the 54 necropsies: mainly pulmonary haemorrhage, aspiration pneumonia, and bronchopneumonia, particularly of the right upper lobe. Adrenal haemorrhage and renal vein thrombosis also occurred.
在125例经临床研究的新生儿破伤风病例中，75例死亡。体温过低和支气管肺炎是导致死亡的最常见原因。所需镇静剂用量突然减少、破伤风体征消失或减弱以及体温过低通常提示支气管肺炎的发生。后来的一组108例病例中有75例死亡（54例行尸检），构成了一项病理学研究的基础。在54例尸检中有46例发现肺部病变：主要是肺出血、吸入性肺炎和支气管肺炎，尤其是右上叶。肾上腺出血和肾静脉血栓形成也有发生。
