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采用单剂量大剂量破伤风抗毒素于脐周皮下注射治疗新生儿破伤风。

Tetanus neonatorum treated by a single high dose of A.T.S. subcutaneously around umbilicus.

作者信息

Rathore A H, Vreebrug A E

出版信息

J Pak Med Assoc. 1978 Jan;28(1):3-6.

PMID:96285
Abstract

Thirteen cases of neonatal tetanus were treated conservatively between 1976 and 1977. A single dose of A.T.S. was infiltrated subcutaneously around the umbilicus and sedation and antibiotics were given as required along with special nursing care. In a previous study (Rathore 1976) large amounts of A.T.S. were given in divided doses by both intravenous and intramuscular routes, the mortality rate was 74 per cent, while in the present series the mortality was reduced to 30.7 per cent.

摘要

1976年至1977年间,对13例新生儿破伤风患者进行了保守治疗。在脐周皮下注射了单剂量的破伤风抗血清,并根据需要给予镇静剂、抗生素以及特殊护理。在之前的一项研究中(拉托尔,1976年),通过静脉和肌肉注射途径分剂量给予大量破伤风抗血清,死亡率为74%,而在本系列研究中,死亡率降至30.7%。

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