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704例未经挑选患者的胆管结石机械碎石术结果

Outcome of mechanical lithotripsy of bile duct stones in an unselected series of 704 patients.

作者信息

Hintze R E, Adler A, Veltzke W

机构信息

Department of Medicine, Virchow-Klinikum, Humboldt-University of Berlin, Germany.

出版信息

Hepatogastroenterology. 1996 May-Jun;43(9):473-6.

PMID:8799379
Abstract

BACKGROUND/AIMS: This paper evaluates the potential benefit of non mechanical bile duct stone lithotripsy techniques. The efficacy, limitations and risks of mechanical lithotripsy as first choice procedure were studied.

MATERIAL AND METHODS

Endoscopic sphincterotomy was performed by Erlangen-type papillotomes, stone extraction by Olympus baskets and mechanical lithotripsy by the Wurbs-system. In an unselected series of 704 patients, everyone with common bile and hepatic duct stones (independent of size, number, location and stone consistency) was included in the study.

RESULTS

Complete stone clearance by endoscopic sphincterotomy and basket extraction was possible in 87.6%. Additional mechanical lithotripsy led to a success rate of 98.4% and in combination with ESWL of 98.5%. In 11 patients without possibility of endoscopic stone removal (1.6%), 4 had no access transpapillary (B-II-situs or duodenal diverticulum), 5 anatomical problems (S-shaped common bile duct, intrahepatic stones or impacted stones in cystic duct orifice), and 2 refused further endoscopic interventions. Complication rate was 1.4% (thereof 1.1% successful treatment by endoscopic or surgical means), lethality rate 0.3%.

CONCLUSIONS

A very high rate of stone clearance by standard endoscopic procedures is possible. In those patients where mechanical lithotripsy is not successful, other non-surgical lithotriptic procedures either cannot be applied because of anatomical reasons or if performed, the improvement in success rate is marginal.

摘要

背景/目的:本文评估非机械性胆管结石碎石技术的潜在益处。研究了作为首选方法的机械碎石术的疗效、局限性和风险。

材料与方法

采用埃尔朗根型乳头切开刀进行内镜括约肌切开术,使用奥林巴斯网篮进行结石取出,并使用伍布斯系统进行机械碎石术。在一组未经选择的704例患者中,所有患有胆总管和肝管结石(不论大小、数量、位置和结石质地)的患者均纳入研究。

结果

通过内镜括约肌切开术和网篮取出实现完全结石清除的比例为87.6%。额外的机械碎石术使成功率达到98.4%,与体外冲击波碎石术联合使用时成功率为98.5%。在11例无法通过内镜取出结石的患者中(1.6%),4例无法经乳头进入(B-II型位置或十二指肠憩室),5例存在解剖学问题(S形胆总管、肝内结石或胆囊管开口处嵌顿结石),2例拒绝进一步的内镜干预。并发症发生率为1.4%(其中1.1%通过内镜或手术手段成功治疗),致死率为0.3%。

结论

通过标准内镜程序可实现很高的结石清除率。在那些机械碎石术不成功的患者中,由于解剖学原因,其他非手术碎石程序要么无法应用,要么即使应用,成功率提高也很有限。

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