Tarter R E, McBride H, Buonpane N, Schneider D U
Arch Gen Psychiatry. 1977 Jul;34(7):761-8. doi: 10.1001/archpsyc.1977.01770190023002.
Alcoholics were differentiated into two subgroups on the basis of drinking patterns and subjective response to alcohol. Severe drinkers (primary alcoholics) retrospectively reported more symptoms of childhood minimal brain dysfunction than less severe drinkers (secondary alcoholics), psychiatric patients, and normals. The alcoholics as a group reported a greater incidence of familial alcohol abuse than the psychiatric subjects, but a difference on this factor was not observed between the primary and secondary subgroups. In terms of clinical status, the primary alcoholics presented Minnesota Multiphasic Personality Inventory profile more indicative of normality than the other groups, but scored significantly higher on the MacAndrew Alcoholism Scale. These findings are discussed in light of further delineating a specific subtype of alcoholism that may have a genetic-constitutional relationship with other pathological disorders.
根据饮酒模式和对酒精的主观反应，酗酒者被分为两个亚组。重度饮酒者（原发性酗酒者）回顾性报告的童年期轻微脑功能障碍症状比轻度饮酒者（继发性酗酒者）、精神科患者和正常人更多。作为一个群体，酗酒者报告的家族性酒精滥用发生率高于精神科受试者，但在原发性和继发性亚组之间未观察到该因素存在差异。在临床状态方面，原发性酗酒者的明尼苏达多相人格问卷剖面图比其他组更显示为正常，但在麦克安德鲁酒精中毒量表上得分显著更高。根据进一步界定可能与其他病理障碍存在遗传体质关系的特定酒精中毒亚型来讨论这些发现。
