Al-Sheyyab M, El-Shanti H, Ajlouni S, Sawalha D, Daoud A
Department of Paediatrics, Jordan University of Science and Technology, Irbid.
Eur J Pediatr. 1995 Dec;154(12):969-72. doi: 10.1007/BF01958639.
Henoch-Schönlein purpura is a common cause of childhood vasculitis. The rarity of the disease under 2 years of age has been the subject of few reports. We present the clinical spectrum of Henoch-Schönlein purpura in 12 children younger than 2 years of age at presentation. The median age at presentation was 11 months. The purpuric skin rash was present in all patients and involved the face in 10 of them. While oedema was a prominent feature in all of our patients only one third had involvement of the kidneys, gastro-intestinal tract or joints. All patients recovered completely after a mean duration of follow up of 10.6 months (range 2-39 months).
Henoch-Schönlein purpura under the age of 2 years is characterized clinically by oedema and a purpuric skin rash which frequently affects the face. Involvement of the joints, kidneys and gastro-intestinal tract is uncommon and the prognosis is excellent. The clinical spectrum in this age group is a continuation with that of Henoch-Schönlein purpura in older children suggesting a nosological entity.
过敏性紫癜是儿童血管炎的常见病因。2岁以下该疾病的罕见性鲜有报道。我们呈现了12例发病时年龄小于2岁的过敏性紫癜患儿的临床特征。发病时的中位年龄为11个月。所有患者均出现紫癜性皮疹，其中10例累及面部。虽然水肿是所有患者的突出特征，但只有三分之一的患者累及肾脏、胃肠道或关节。所有患者在平均随访10.6个月（范围2 - 39个月）后完全康复。
2岁以下的过敏性紫癜临床特征为水肿和紫癜性皮疹，且皮疹常累及面部。关节、肾脏和胃肠道受累并不常见，预后良好。该年龄组的临床特征与大龄儿童过敏性紫癜的特征相连续，提示为同一病种。
