Sulston J E
Philos Trans R Soc Lond B Biol Sci. 1976 Aug 10;275(938):287-97. doi: 10.1098/rstb.1976.0084.
56 nerve cells are added to the ventral cord and associated ganglia of Caenorhabditis elegans at about the time of the first larval moult. These cells are produced by the uniform division of 13 neuroblasts followed by a defined pattern of cell deaths. Comparison with the data in the previous paper suggests that there is a relationship between the ancestry of a cell and its function. The significance of programmed cell death is discussed.
在秀丽隐杆线虫首次幼虫蜕皮时,约有56个神经细胞添加到腹神经索和相关神经节中。这些细胞由13个神经母细胞均匀分裂产生,随后是特定模式的细胞死亡。与前一篇论文中的数据比较表明,细胞的谱系与其功能之间存在关联。文中讨论了程序性细胞死亡的意义。