Nakatsuka H, Ueda T, Ohta S, Sakaki S
Department of Neurological Surgery, Ehime University School of Medicine, Japan.
Neurosurgery. 1996 Jul;39(1):161-4. doi: 10.1097/00006123-199607000-00034.
We report our experience with low-pressure submaximal percutaneous transluminal angioplasty (PTA) for basilar artery stenosis of > 90%. This treatment resulted in a favorable clinical course and satisfactory improvement of posterior cerebral circulation.
This technique was applied to two patients with repeated basilar arterial ischemic symptoms that were resistant to medical treatment.
Low-pressure submaximal PTA was performed with use of a smaller balloon (2.0-mm diameter) and lower inflation pressure (< or = 303,975 Pa) than previously reported.
Despite basilar arteries with 50 and 60% residual stenosis, the clinical symptoms and hemodynamics in the basilar arterial territory as assessed using single photon emission tomography were markedly improved after PTA. Follow-up angiographic evaluation demonstrated the absence of restenosis, and improved cerebral blood flow was maintained. Neither patient has developed any new neurological deficits 10 and 13 months after the PTA, respectively.
Submaximal PTA may have reduced the high risk associated with this procedure, and cerebral blood flow measurement may be a useful tool to assess whether this technique will produce adequate results.
我们报告了对基底动脉狭窄超过90%的患者进行低压次最大剂量经皮腔内血管成形术(PTA)的经验。该治疗产生了良好的临床病程,后循环得到了令人满意的改善。
该技术应用于两名反复出现基底动脉缺血症状且药物治疗无效的患者。
使用比先前报道更小的球囊(直径2.0毫米)和更低的充盈压力(≤303,975帕)进行低压次最大剂量PTA。
尽管基底动脉残留狭窄分别为50%和60%,但经单光子发射断层扫描评估,PTA后基底动脉区域的临床症状和血流动力学明显改善。随访血管造影评估显示无再狭窄,脑血流量持续改善。两名患者在PTA后分别于10个月和13个月均未出现任何新的神经功能缺损。
次最大剂量PTA可能降低了该手术相关的高风险,脑血流量测量可能是评估该技术是否会产生足够效果的有用工具。