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五十岁以下女性进行乳房筛查的价值。

The value of breast screening in women less than fifty years of age.

作者信息

Letton A H, Wilson J P, Mason E M

出版信息

Cancer. 1977 Jul;40(1):1-3. doi: 10.1002/1097-0142(197707)40:1<1::aid-cncr2820400102>3.0.co;2-#.

Abstract

In the four years our Breast Cancer Detection Demonstration Project has been receiving patients, 5,810 women under the age of fifty have been examined. Our findings definitely indicate screening of asymptomatic women by xeromammography is of advantage in this group whose greatest cause of death is cancer of the breast; 71.8% of their cancers were found by xeromammography. Of these 43.8% had in situ cancer and only 12.5% of those cancers found had axillary spread. This group should have a five-year cure rate of 87.1% rather than 63% as is the experience of unscreened women. The absorbed rads averaged 0.4632 to each breast per year. At the end of five years this would cause an estimated increase in risk from 7% to 7.162%. To increase survival rate by 24.1% against a theoretical increased risk of 0.16% is definitely worthwhile.

摘要

在我们的乳腺癌检测示范项目接收患者的四年里,对5810名50岁以下的女性进行了检查。我们的研究结果明确表明,对无症状女性进行干板乳房X线照相筛查对该群体具有优势,因为她们最大的死因是乳腺癌;她们71.8%的癌症是通过干板乳房X线照相发现的。其中43.8%为原位癌,而这些发现的癌症中只有12.5%有腋窝转移。该群体的五年治愈率应为87.1%,而不是未筛查女性所经历的63%。每个乳房每年平均吸收0.4632拉德。五年后,这将导致估计风险从7%增加到7.162%。将生存率提高24.1%以应对理论上0.16%的风险增加绝对是值得的。

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