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两个鸡重复元件1(CR1),在鸡抗生物素蛋白相关基因Avr4和Avr5上游缺乏类似沉默子的区域。

Two chicken repeat one (CR1) elements lacking a silencer-like region upstream of the chicken avidin-related genes Avr4 and Avr5.

作者信息

Wallén M J, Keinänen R A, Kulomaa M S

机构信息

Department of Biomedical Sciences, University of Tampere, Finland.

出版信息

Biochim Biophys Acta. 1996 Sep 11;1308(3):193-6. doi: 10.1016/0167-4781(96)00119-4.

Abstract

Two repetitive elements of the chicken CR1 family, each located in the 5' flanking region of the avidin-related genes Avr4 and Avr5, have been cloned and sequenced. Both elements are 721 bp in length with 72% identity to a CR1 consensus sequence. They had a 191 bp deletion in a region corresponding to the functional silencer regions previously detected within the CR1 elements upstream of the chicken lysozyme and apoVLDLII genes.

摘要

鸡CR1家族的两个重复元件已被克隆和测序,它们分别位于抗生物素蛋白相关基因Avr4和Avr5的5'侧翼区域。这两个元件长度均为721 bp,与CR1共有序列的一致性为72%。在与先前在鸡溶菌酶和载脂蛋白VLDLII基因上游的CR1元件中检测到的功能沉默区域相对应的区域,它们有一个191 bp的缺失。

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