• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

针对HLA-D相关(DR)抗原的同种异体抗血清对T细胞介导的细胞溶解的特异性抑制作用。

Specific inhibition of T-cell-mediated cytolosis by alloantiserum against HLA-D-related (DR) antigens.

作者信息

Feighery C F, Stastny P

出版信息

Transplant Proc. 1979 Mar;11(1):708-11.

PMID:88098
Abstract

Lymphocytes sensitized against HLA-A and B region-compatible, HLA-D region-incompatible stimulators were cytotoxic for target cells having the correct HLA-D antigens. This form of cytotoxicity was inhibited by platelet-absorbed pregnancy sera containing antibodies to the HLA-DR antigens of the target cells but not by sera with antibodies against other DR antigens. This form of CML was also inhibited by unlabeled monocytes and B cells of the relevant HLA-D specificity but not by T lymphocytes from the same donors.

摘要

对HLA - A和B区域相容、HLA - D区域不相容的刺激物致敏的淋巴细胞,对具有正确HLA - D抗原的靶细胞具有细胞毒性。这种细胞毒性形式被含有针对靶细胞HLA - DR抗原抗体的血小板吸收妊娠血清所抑制,但不被含有针对其他DR抗原抗体的血清所抑制。这种形式的慢性粒细胞白血病也被具有相关HLA - D特异性的未标记单核细胞和B细胞所抑制,但不被来自相同供体的T淋巴细胞所抑制。

相似文献

1
Specific inhibition of T-cell-mediated cytolosis by alloantiserum against HLA-D-related (DR) antigens.针对HLA-D相关(DR)抗原的同种异体抗血清对T细胞介导的细胞溶解的特异性抑制作用。
Transplant Proc. 1979 Mar;11(1):708-11.
2
[Differences in the capacity of HLA sera to react with T- and B-lymphocyte populations].[人类白细胞抗原血清与T淋巴细胞和B淋巴细胞群体反应能力的差异]
Biull Eksp Biol Med. 1976 Jun;81(6):698-9.
3
Dilutions and specificity analysis of pretransplant sera.移植前血清的稀释及特异性分析。
Transplant Proc. 1979 Mar;11(1):944-9.
4
Characterization of B-cell and monocyte antibodies in recipient sera and in eluates from rejected kidney allografts.受体血清及排斥肾移植受者洗脱液中B细胞和单核细胞抗体的特征分析。
Transplant Proc. 1981 Mar;13(1 Pt 1):111-3.
5
Genetic restriction of autoreactive acetylcholine receptor-specific T lymphocytes in myasthenia gravis.重症肌无力中自身反应性乙酰胆碱受体特异性T淋巴细胞的遗传限制
J Immunol. 1985 Oct;135(4):2393-9.
6
A suppressor T cell of the mixed lymphocyte reaction specific for the HLA-D region in man.人混合淋巴细胞反应中针对HLA - D区域的抑制性T细胞。
J Clin Invest. 1978 Mar;61(3):828-38. doi: 10.1172/JCI108997.
7
Cell-mediated cytotoxicity against HLA-D-region products expressed in monocytes and B lymphocytes. I. Blocking by Unlabelled cells and inhibition by antisera.针对单核细胞和B淋巴细胞中表达的HLA - D区产物的细胞介导细胞毒性。I. 未标记细胞的阻断作用和抗血清的抑制作用。
Immunogenetics. 1980;10(1):31-8. doi: 10.1007/BF01561550.
8
HLA-DR-restricted cytotoxicity of cytomegalovirus-infected monocytes mediated by Leu-3-positive T cells.由Leu-3阳性T细胞介导的巨细胞病毒感染单核细胞的HLA-DR限制性细胞毒性。
J Immunol. 1986 Apr 15;136(8):3045-51.
9
Specificity of mouse cytotoxic T lymphocytes stimulated with either HLA-A and -B or HLA-DR antigens reconstituted into phospholipid vesicles.用重组到磷脂囊泡中的HLA - A和 - B或HLA - DR抗原刺激的小鼠细胞毒性T淋巴细胞的特异性。
J Exp Med. 1980 Aug 1;152(2 Pt 2):54s-64s.
10
[Kinetics of the appearance of HLA-DR antigens on human alloactivated T lymphocytes and the demonstration of new antigenic determinants].[人类同种异体激活的T淋巴细胞上HLA - DR抗原出现的动力学及新抗原决定簇的证明]
C R Seances Acad Sci D. 1980 Nov 3;291(9):757-61.