Wunder A, Anke T, Klostermeyer D, Steglich W
LB Biotechnologie der Universität, Kaiserslautern, Bundesrepublik Deutschland.
Z Naturforsch C J Biosci. 1996 Jul-Aug;51(7-8):493-9.
Three known sesquiterpenoids of the lactarane and secolactarane type, deoxylactarorufin A (1), blennin A (2) and blennin C (3), have been obtained from cultures of Lentinellus cochleatus (Basidiomycetes) together with the new metabolites (Z)-2-chloro-3-(4-methoxyphenyl)-2-propen-1-ol (4) and lentinellone (5), a protoilludane derivative. The structures were determined by spectroscopic investigations. 1, 2 and 3 are potent inhibitors of leukotriene biosynthesis in rat basophilic leukemia (RBL-1) cells and human peripheral blood leukocytes (PBL).
从皱盖乌芝（担子菌纲）的培养物中获得了三种已知的乳菇烷型和降乳菇烷型倍半萜类化合物，即脱氧乳菇红菌素A（1）、黏菌素A（2）和黏菌素C（3），以及新的代谢产物（Z）-2-氯-3-（4-甲氧基苯基）-2-丙烯-1-醇（4）和原伊鲁烷衍生物香菇酮（5）。通过光谱研究确定了其结构。1、2和3是大鼠嗜碱性白血病（RBL-1）细胞和人外周血白细胞（PBL）中白三烯生物合成的有效抑制剂。
