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人己糖激酶III cDNA序列及通过荧光原位杂交将人己糖激酶III基因(HK3)定位于染色体5q35.2带

Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization.

作者信息

Furuta H, Nishi S, Le Beau M M, Fernald A A, Yano H, Bell G I

机构信息

Department of Medicine, The University of Chicago, Chicago, Illinois, 60637, USA.

出版信息

Genomics. 1996 Aug 15;36(1):206-9. doi: 10.1006/geno.1996.0448.

Abstract

Complementary DNA clones encoding human hexokinase III were isolated from a liver cDNA library. There was 84.7% identity between the amino acid sequences of human and rat hexokinase III. RNA blotting showed the presence of hexokinase III mRNA in liver and lung. Fluorescence in situ hybridization localized the human hexokinase III gene (HK3) to chromosome 5, band q35.2.

摘要

从肝脏cDNA文库中分离出编码人己糖激酶III的互补DNA克隆。人和大鼠己糖激酶III的氨基酸序列之间有84.7%的同一性。RNA印迹显示肝脏和肺中存在己糖激酶III mRNA。荧光原位杂交将人己糖激酶III基因(HK3)定位到5号染色体q35.2带。

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