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Carnitine effect on heart steatosis induced in rats by rapeseed oil.

作者信息

Branca D, Scutari G, Siliprandi N

出版信息

Int J Vitam Nutr Res. 1977;47(2):162-6.

PMID:881297
Abstract

Myocardial triglyceride levels in rats fed a high erucic acid rapeseed oil diet for three days were five times higher than in controls. The incorporation of erucic acid and, to a lower extent, some unsaturated fatty acids was increased, as well as total cholesterol content, compared to controls. The presence of 5% carnitine in the diet partially prevented these effects. It is assumed that carnitine may be a rate limiting factor in the myocardial catabolism of unsaturated fatty acids and particularly erucic acid, when these substance are ingested in supraoptimal amount.

摘要

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