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[n-9反式二十二碳烯酸(芜酸)和n-9顺式二十二碳烯酸(芥酸)对断奶大鼠心脏脂质影响的短期比较研究]

[Short term comparative study of effects of n-9 trans-docosenoic (brassidic) acid and n-9, cis-docosenoic (erucic) acid on the cardiac lipids of weanling rats].

作者信息

Rocquelin G, Juaneda P, Péleran J C, Astorg P O

出版信息

Nutr Metab. 1975;19(3-4):113-26.

PMID:1230664
Abstract

Cardiac lipids (triglycerides and phospholipids) of weanling rats fed diets containing 15% by weight of rapeseed oil (RSO), hydrogenated rapeseed oil (HRSO), trierucin (TE) or tribassidin (TB) were analyzed after 3 and 7 days of feeding. The amount of C22:1 was made equal in the 4 diets. Trans-isomers of erucic acid found in HRSO and TB do not cause as high an accumulation of lipids and docosenoic acids in the heart as erucic acid. Digestibility of brassidic acid (46%) is lower than that or erucic acid (83%) but even then, the amount of brassidic acid found in cardiac lipids (calculated per gram of absorbed fatty acid) after 7 days of feeding is 10 times less than that of erucic acid. Brassidic acid, like erucic acid, can be converted into shorter monoenes (C20:1 and C18:1) since transC18:1 has been found in cardiac phospholipids of rats fed trans-docosenoic acid as the only source of trans-acid in the diet.

摘要

在以含15%(重量)菜籽油(RSO)、氢化菜籽油(HRSO)、甘油三芥酸酯(TE)或三巴豆油(TB)的日粮喂养断奶大鼠3天和7天后,分析其心脏脂质(甘油三酯和磷脂)。使4种日粮中的C22:1含量相等。在HRSO和TB中发现的芥酸反式异构体在心脏中引起的脂质和二十二碳烯酸积累量不如芥酸高。油菜酸(46%)的消化率低于芥酸(83%),但即便如此,喂养7天后在心脏脂质中发现的油菜酸量(按每克吸收的脂肪酸计算)比芥酸少10倍。与芥酸一样,油菜酸也可转化为较短的单烯酸(C20:1和C18:1),因为在以反式二十二碳烯酸作为日粮中反式酸唯一来源喂养的大鼠心脏磷脂中发现了反式C18:1。

相似文献

1
[Short term comparative study of effects of n-9 trans-docosenoic (brassidic) acid and n-9, cis-docosenoic (erucic) acid on the cardiac lipids of weanling rats].[n-9反式二十二碳烯酸(芜酸)和n-9顺式二十二碳烯酸(芥酸)对断奶大鼠心脏脂质影响的短期比较研究]
Nutr Metab. 1975;19(3-4):113-26.
2
[Comparison of mean-term physiological effects of cis and trans docosenoic acids in the rat. II. Effects on the lipids and fatty acids of plasma, adipose tissue, liver and heart].[顺式和反式二十二碳烯酸对大鼠中期生理效应的比较。II. 对血浆、脂肪组织、肝脏和心脏脂质及脂肪酸的影响]
Ann Nutr Aliment. 1979;33(5):659-86.
3
[Comparison of the mean-term physiological effects of cis or trans docosenoic acids in the rat. I. Digestibility of fatty acids. Effects on growth, organ weights and heart histology].[顺式或反式二十二碳烯酸对大鼠中期生理效应的比较。I. 脂肪酸的消化率。对生长、器官重量和心脏组织学的影响]
Ann Nutr Aliment. 1979;33(5):643-58.
4
[Comparative short-term incorporation of n-9 trans docosenoic (brassidic) and n-9 cis-docosenoic (erucic) acids into rat adipose tissue].
C R Seances Soc Biol Fil. 1976;170(5):1051-6.
5
[Effects of conjugates of linolenic acid and erucic acid on rat cardiac and liver lipids].
Nutr Metab. 1979;23(2):98-108.
6
[Short term effects of docosenoic acid-containing oils on rat cardiac lipids: colza oil and partially hydrogenated herring oil].
C R Seances Soc Biol Fil. 1975;169(4):966-70.
7
[Comparative digestive utilization and forms of fecal excretion in the rat of erucic and brassidic acids esterified in different glyceride structures].[芥酸和油菜酸在不同甘油酯结构中酯化后在大鼠体内的比较消化利用率及粪便排泄形式]
Reprod Nutr Dev (1980). 1980;20(5A):1415-27.
8
[Digestive utilization of cis and trans docosenoic acids in the rat: effects of dietary levels of calcium and linoleic acid].
Ann Nutr Aliment. 1980;34(4):625-40.
9
Heart lipidosis induced by short-term feeding of cis- or trans-docosenoic acids in weanling or 7-week-old rats.
Ann Nutr Metab. 1981;25(4):201-7. doi: 10.1159/000176495.
10
[Effect of alcohol on the metabolic conversion of 14C erucic acid in the liver of rats receiving rapeseed or peanut oil].[酒精对摄入菜籽油或花生油的大鼠肝脏中14C芥酸代谢转化的影响]
J Physiol (Paris). 1975;70(4):493-503.

引用本文的文献

1
The effects of partially hydrogenated marine oils on the mitochondrial function and membrane phospholipid fatty acids in rat heart.部分氢化海洋油对大鼠心脏线粒体功能和膜磷脂脂肪酸的影响。
Lipids. 1983 Mar;18(3):151-70. doi: 10.1007/BF02534543.
2
Nutritional effects of partially hydrogenated low erucic rapeseed oils.部分氢化低芥酸菜籽油的营养作用
Lipids. 1977 Oct;12(10):769-74. doi: 10.1007/BF02533263.
3
Comparison of lipid status in the hearts of piglets and rats on short term feeding of marine oils and rapeseed oils.
Lipids. 1979 Apr;14(4):356-71. doi: 10.1007/BF02533419.