Kawano M, Muramoto H, Tsunoda S, Koni I, Mabuchi H, Yachie A, Miyawaki T
Second Department of Internal Medicine, Kanazawa University, Japan.
Am J Hematol. 1996 Sep;53(1):43-5. doi: 10.1002/(SICI)1096-8652(199609)53:1<43::AID-AJH10>3.0.CO;2-4.
A 45-year-old woman with episodic angioedema and eosinophilia is presented. CD69, which is one of the surface antigens of activated eosinophils, was not expressed on the peripheral eosinophils in this patient, in contrast to hypereosinophilic syndrome. This suggests that CD69, which is not dependent on eosinophil density, may be another useful activation marker of eosinophils to distinguish episodic angioedema and eosinophilia from hypereosinophilic syndrome.
本文报告了一名患有发作性血管性水肿和嗜酸性粒细胞增多症的45岁女性。与高嗜酸性粒细胞综合征不同，活化嗜酸性粒细胞的表面抗原之一CD69在该患者的外周嗜酸性粒细胞上未表达。这表明，不依赖于嗜酸性粒细胞密度的CD69可能是另一种有用的嗜酸性粒细胞活化标志物，可用于区分发作性血管性水肿和嗜酸性粒细胞增多症与高嗜酸性粒细胞综合征。
