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生长抑素类似物与胰腺外分泌

Somatostatin analogues and exocrine pancreatic secretion.

作者信息

Gullo L

机构信息

Department of Medicine and Gastroenterology, University of Bologna, St. Orsola Hospital, Italy.

出版信息

Digestion. 1996;57 Suppl 1:93. doi: 10.1159/000201408.

Abstract

Subcutaneous injection of 50 micrograms octreotide before a meal can almost totally prevent the increase in exocrine pancreatic secretions caused by the meal. Octreotide inhibits plasma amino acid uptake by pancreatic acinar cells, and thus synthesis of pancreatic enzymes. This effect has clinical potential.

摘要

饭前皮下注射50微克奥曲肽几乎可以完全防止进餐引起的胰腺外分泌增加。奥曲肽抑制胰腺腺泡细胞摄取血浆氨基酸,从而抑制胰腺酶的合成。这一作用具有临床应用潜力。

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