Putz G, Hörmann C, Koller W, Schön G
Division of Surgical and General Intensive Care Medicine, Clinic for Anesthesia, General Intensive Care Medicine, Innsbruck, Austria.
Intensive Care Med. 1996 Jun;22(6):588-90. doi: 10.1007/BF01708102.
A modified natural surfactant was administered to a patient with life-threatening adult respiratory distress syndrome caused by viral pneumonia. Subsequently, there was a marked improvement in gas exchange. In order to assess the mechanism for improved oxygenation, computed tomography of the lungs was done. Quantitative analysis of the scans taken before and after surfactant administration indicates that improvement in gas exchange was largely due to the expansion of underinflated and collapsed lung areas. Although this is a single case report, it provides insight into the possible beneficial effect of instilled surfactant in severe respiratory distress from viral pneumonia.
一种改良的天然表面活性剂被给予一名因病毒性肺炎导致危及生命的成人呼吸窘迫综合征的患者。随后，气体交换有了显著改善。为了评估氧合改善的机制，对肺部进行了计算机断层扫描。对表面活性剂给药前后所做扫描的定量分析表明，气体交换的改善很大程度上归因于未充分膨胀和塌陷的肺区域的扩张。尽管这是一份单病例报告，但它为注入表面活性剂对病毒性肺炎所致严重呼吸窘迫可能产生的有益作用提供了见解。
