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肺癌中锝-99m替曲膦摄取情况:与铊-201的比较

Technetium-99m tetrofosmin uptake in lung cancer: comparison with thallium-201.

作者信息

Matsunari I, Kinuya S, Nishikawa T, Matoba M, Murakita K, Ohguchi M, Ichiyanagi K, Taki J, Tonami N, Hisada K

机构信息

Department of Radiology, Fukui Prefectual Hospital.

出版信息

Ann Nucl Med. 1996 Feb;10(1):143-5. doi: 10.1007/BF03165069.

DOI:10.1007/BF03165069
PMID:8814720
Abstract

Technetium-99m tetrofosmin and thallium-201 lung SPECT imaging were performed in a patient with adenocarcinoma of the lung. Significant activities in the lung lesion were clearly depicted on both technetium-99m tetrofosmin and thallium-201 SPECT imaging. The early uptake, delayed uptake ratios and retention indices of the tumor were 2.75, 2.39 and -1.31 for thallium-201 imaging and 3.09, 2.27 and -26.5 for technetium-99m tetrofosmin imaging, respectively. This preliminary report suggests that technetium-99m tetrofosmin may have potential as a tumor imaging agent.

摘要

对一名肺癌腺癌患者进行了锝-99m替曲膦和铊-201肺部单光子发射计算机断层显像(SPECT)检查。在锝-99m替曲膦和铊-201 SPECT显像上均清晰显示出肺部病变中有明显放射性浓聚。铊-201显像时肿瘤的早期摄取、延迟摄取率和滞留指数分别为2.75、2.39和-1.31,锝-99m替曲膦显像时分别为3.09、2.27和-26.5。这份初步报告表明,锝-99m替曲膦可能具有作为肿瘤显像剂的潜力。

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Technetium-99m tetrofosmin uptake in lung cancer: comparison with thallium-201.肺癌中锝-99m替曲膦摄取情况:与铊-201的比较
Ann Nucl Med. 1996 Feb;10(1):143-5. doi: 10.1007/BF03165069.
2
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Tomographic myocardial imaging with technetium-99m tetrofosmin. Comparison with tetrofosmin and thallium planar imaging and with angiography.锝-99m 替曲膦的断层心肌显像。与替曲膦和铊平面显像及血管造影的比较。
Eur Heart J. 1996 Apr;17(4):635-42. doi: 10.1093/oxfordjournals.eurheartj.a014919.

本文引用的文献

1
Technetium-99m-tetrofosmin as a new radiopharmaceutical for myocardial perfusion imaging.锝-99m-替曲膦作为一种用于心肌灌注显像的新型放射性药物。
J Nucl Med. 1993 Feb;34(2):222-7.
2
Technetium-99m-1,2-bis[bis(2-ethoxyethyl) phosphino]ethane: human biodistribution, dosimetry and safety of a new myocardial perfusion imaging agent.锝-99m-1,2-双[双(2-乙氧基乙基)膦基]乙烷:一种新型心肌灌注显像剂的人体生物分布、剂量学及安全性
J Nucl Med. 1993 Jan;34(1):30-8.
3
Differentiation of single solid lesions in the lungs by means of single-photon emission tomography with technetium-99m methoxyisobutylisonitrile.
Eur J Nucl Med. 1993 Mar;20(3):249-54. doi: 10.1007/BF00170007.
4
Biokinetics of technetium-99m-tetrofosmin: myocardial perfusion imaging agent: implications for a one-day imaging protocol.
J Nucl Med. 1993 Aug;34(8):1254-9.
5
Tracer imaging in lung cancer.肺癌中的示踪成像。
Eur J Nucl Med. 1994 Jan;21(1):57-81. doi: 10.1007/BF00182307.
6
Primary lung cancer SPECT imaging with pentavalent technetium-99m-DMSA.用五价锝-99m-二巯基丁二酸进行原发性肺癌单光子发射计算机断层显像
J Nucl Med. 1995 Feb;36(2):202-7.
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Uptake and kinetics of Tc-99m hexakis 2-methoxy isobutyl isonitrile in benign and malignant lesions in the lungs.
Clin Nucl Med. 1989 May;14(5):333-40. doi: 10.1097/00003072-198905000-00005.
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Thallium-201 single photon emission computed tomography in the evaluation of suspected lung cancer.
J Nucl Med. 1989 Jun;30(6):997-1004.