Murguía de Sierra T, Florido J, Muñoz T, Arriola M, Palafox H, Sierra-Madero J G
Departamento de Neonatología, Hospital Infantil de México Federico Gómez, México D.F.
Rev Invest Clin. 1996 Jan-Feb;48(1):35-41.
We describe a newborn patient with herpes simplex infection localized to the central nervous system. The diagnosis was suspected on clinical grounds and it was corroborated by tissue culture isolation of the virus and by herpes simplex glycoprotein B DNA detection by PCR in cerebrospinal fluid. We describe the clinical manifestations of this patient and we present some considerations regarding pathogenesis, diagnosis, prognosis and treatment of this viral infection in the newborn period.
我们描述了一名患有单纯疱疹感染且局限于中枢神经系统的新生儿患者。临床怀疑该诊断,并通过病毒的组织培养分离以及脑脊液中单纯疱疹病毒糖蛋白B的PCR检测得以证实。我们描述了该患者的临床表现,并就新生儿期这种病毒感染的发病机制、诊断、预后和治疗提出了一些思考。