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犬G带核型标准化进展报告。犬(家犬)核型标准化委员会。

Report on the progress of standardization of the G-banded canine (Canis familiaris) karyotype. Committee for the Standardized Karyotype of the Dog (Canis familiaris).

作者信息

Switoński M, Reimann N, Bosma A A, Long S, Bartnitzke S, Pieńkowska A, Moreno-Milan M M, Fischer P

机构信息

Department of Genetics and Animal Breeding, Agricultural University of Poznan, Poland.

出版信息

Chromosome Res. 1996 Jun;4(4):306-9. doi: 10.1007/BF02263682.

DOI:10.1007/BF02263682
PMID:8817072
Abstract

Karyotyping of dog chromosomes is a difficult task owing to the high diploid number of chromosomes (2n = 78) and the similar morphology of autosomes, all of which are acrocentrics. In this report 22 of the 39 G-banded chromosome pairs and their corresponding ideograms have been standardized. The ideogram comprises altogether 235 bands. The need for the introduction of molecular techniques such as chromosome painting and physical mapping of genetic markers for the identification of small acrocentrics is discussed.

摘要

由于犬类染色体的二倍体数目很高(2n = 78)且常染色体形态相似,均为近端着丝粒染色体,因此对犬染色体进行核型分析是一项艰巨的任务。在本报告中,39对G带染色体中的22对及其相应的 ideogram已被标准化。该ideogram总共包含235条带。讨论了引入诸如染色体涂染和遗传标记的物理图谱绘制等分子技术以鉴定小近端着丝粒染色体的必要性。

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本文引用的文献

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Mamm Genome. 1996 Jan;7(1):37-41. doi: 10.1007/s003359900009.
2
Chromosome-specific paints from a high-resolution flow karyotype of the dog.来自犬高分辨率流式核型分析的染色体特异性涂染剂。
Chromosome Res. 1996 Feb;4(2):115-23. doi: 10.1007/BF02259704.
3
Evidence that metacentric and submetacentric chromosomes in canine tumors can result from telomeric fusions.犬类肿瘤中的中着丝粒染色体和亚中着丝粒染色体可能由端粒融合产生的证据。
Animals (Basel). 2021 Mar 27;11(4):947. doi: 10.3390/ani11040947.
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Analysis of XX -Negative Sex Reversal Dogs.XX 阴性性反转犬的分析
Animals (Basel). 2020 Sep 16;10(9):1667. doi: 10.3390/ani10091667.
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Structural and copy number chromosome abnormalities in canine cutaneous mast cell tumours.犬皮肤肥大细胞瘤的结构和拷贝数染色体异常。
J Appl Genet. 2019 Feb;60(1):63-70. doi: 10.1007/s13353-018-0471-4. Epub 2018 Oct 4.
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Fluorescence chromosome banding and FISH mapping in perennial ryegrass, Lolium perenne L.多年生黑麦草(Lolium perenne L.)的荧光染色体显带和荧光原位杂交图谱分析
BMC Genomics. 2016 Nov 25;17(1):977. doi: 10.1186/s12864-016-3231-z.
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Copy number variation in the region harboring SOX9 gene in dogs with testicular/ovotesticular disorder of sex development (78,XX; SRY-negative).患有性发育睾丸/卵睾体疾病(78,XX;SRY阴性)的犬类中,SOX9基因所在区域的拷贝数变异。
Sci Rep. 2015 Oct 1;5:14696. doi: 10.1038/srep14696.
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