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免疫球蛋白M血清诊断试验用于急性巴贝斯虫病快速诊断的效能

Efficacy of immunoglobulin M serodiagnostic test for rapid diagnosis of acute babesiosis.

作者信息

Krause P J, Ryan R, Telford S, Persing D, Spielman A

机构信息

Department of Pediatrics, University of Connecticut School of Medicine, Farmington 06030, USA.

出版信息

J Clin Microbiol. 1996 Aug;34(8):2014-6. doi: 10.1128/jcm.34.8.2014-2016.1996.

Abstract

To evaluate the efficacy of an immunoglobulin M indirect immunofluorescent-antibody procedure for diagnosing acute babesiosis, we tested patients with acute babesiosis from a site in New England where the disease is enzootic. The sensitivity of the test was 91%, the specificity was 99%, the positive predictive value was 86%, and the negative predictive value was 99%. This B. microti immunoglobulin M indirect immunofluorescent-antibody procedure is sufficiently sensitive, specific, and reproducible for use in the routine clinical diagnosis of acute babesiosis.

摘要

为评估免疫球蛋白M间接免疫荧光抗体检测法诊断急性巴贝斯虫病的疗效,我们对来自新英格兰一个该病为动物流行病疫区的急性巴贝斯虫病患者进行了检测。该检测的敏感性为91%,特异性为99%,阳性预测值为86%,阴性预测值为99%。这种微小巴贝斯虫免疫球蛋白M间接免疫荧光抗体检测法在敏感性、特异性和可重复性方面足以用于急性巴贝斯虫病的常规临床诊断。

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本文引用的文献

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J Clin Microbiol. 1992 Aug;30(8):2097-103. doi: 10.1128/jcm.30.8.2097-2103.1992.

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