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[血液纠正剂Lactosorbal对严重失血性休克模型犬肝脏功能活性的影响]

[The effect of the blood corrective agent Lactosorbal on liver functional activity in dogs with a model of severe hemorrhagic shock].

作者信息

Oborin A N, Mindiuk M V

出版信息

Lik Sprava. 1995 Mar-Apr(3-4):152-4.

PMID:8819952
Abstract

A new complex action hemocorrective <> was studied for its effect on functional activity of the liver, for which purpose a total of 5 dogs subjected to severe hemorrhagic shock were used. Apart from marked hemodynamic effects the <> intravenous transfusions (10 ml/kg) promote restoration of hepatic functions and survival of animals. Possible modes of action responsible for therapeutic effect of <> are considered. The results of the present study serve to experimentally substentiate the use of <> in combined therapy of grave forms of shock of different genesis during all stages of medical evacuation as well as of acute renal insufficiency in clinical settings.

摘要

研究了一种新型复合作用血液纠正剂《乳糖吸附剂》对肝脏功能活性的影响,为此总共使用了5只遭受严重失血性休克的狗。除了显著的血液动力学效应外,静脉输注《乳糖吸附剂》(10毫升/千克)可促进肝功能的恢复和动物的存活。探讨了《乳糖吸附剂》治疗效果的可能作用方式。本研究结果有助于从实验上证实《乳糖吸附剂》在不同病因严重休克的综合治疗中,在医疗后送的各个阶段以及临床环境中急性肾功能不全的治疗中的应用。

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