[Energetics of the growth of methanol oxidizing yeasts].

The effect of aeration on the economic coefficient and the phosphorylating effectiveness of oxidation was studied during chemostat cultivation of the methanol oxidizing yeast Candida boidinii. Changes in the partial pressure of dissolved oxygen from 0.008 to 0.08 atm caused a decrease in the economic coefficient from 0.40 to 0.25 g of biomass per 1 g of assimilated methanol, and an increase in the uptake of oxygen. The value of P/O, calculated from the ATP balance for biosynthetic processes, decreased from 1.4 to 0.7. The maximum theoretical economic coefficient for the growth of C. boidinii on a medium containing methanol is 0.47 g of biomass formed per 1 g of assimilated methanol.