Eliseeva L G, Gololobov A D, Gracheva I M
Mikrobiologiia. 1977 Mar-Apr;46(2):263-9.
The biosynthesis of lipids by Candida guilliermondii was studied during the growth of the yeast on carbon substrates which resulted in different pathways of lipid biosynthesis. The highest content of lipids was found during the growth on octadecane. The quantitative ratio between fractions of neutral lipids and phospholipids depended on the carbon substrate whereas the quanlitative composition of the fractions remained the same. The fatty acid composition of lipid fractions was studied, and possible pathways of their biosynthesis are discussed. Apparently, the assimilated hydrocarbon is oxidized to acetyl residues in certain structures of the yeast cells while, in other structures, the hydrocarbon substrate undergoes only monoterminal oxidation yielding an aliphatic alcohol and an acid which are directly used in large amounts for the synthesis of wax and triglycerides.
在季也蒙毕赤酵母利用导致不同脂质生物合成途径的碳源生长过程中，对其脂质生物合成进行了研究。在十八烷上生长期间发现脂质含量最高。中性脂质和磷脂组分之间的定量比例取决于碳源，而各组分的定性组成保持不变。研究了脂质组分的脂肪酸组成，并讨论了其生物合成的可能途径。显然，被同化的碳氢化合物在酵母细胞的某些结构中被氧化为乙酰残基，而在其他结构中，碳氢化合物底物仅经历单末端氧化，产生脂肪醇和酸，这些物质大量直接用于蜡和甘油三酯的合成。
