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老年长期护理机构居民皮肤和软组织感染的药物治疗

Drug treatment of skin and soft tissue infections in elderly long-term care residents.

作者信息

Lertzman B H, Gaspari A A

机构信息

Department of Dermatology, University of Rochester School of Medicine and Dentistry, New York 14642, USA.

出版信息

Drugs Aging. 1996 Aug;9(2):109-21. doi: 10.2165/00002512-199609020-00006.

DOI:10.2165/00002512-199609020-00006
PMID:8820797
Abstract

Nursing home-acquired skin and soft tissue infections are common, with an estimated prevalence of approximately 5%. Such infections can be a cause of significant morbidity. The types of organisms that cause primary skin and soft tissue infections in the elderly are diverse, and include bacterial, viral and fungal infections, as well as infestations with scabies or lice. In the elderly, these infections or infestations may present with atypical signs and symptoms, so a high index of suspicion is necessary. These skin and soft tissue infections may complicate an underlying chronic skin disorder (such as a decubitus ulcer), further altering their clinical presentation. Treatment of skin infections and infestations is based on the appropriate diagnostic tests. Once the diagnosis has been confirmed, treatment with the standard drug therapy is usually associated with a favourable clinical outcome. This article summarises the major skin and soft tissue infections in the elderly, and the appropriate drug therapy, with emphasis on special considerations for long-term care residents and the unique environment of the nursing home that allows for the emergence of resistant organisms. These factors make the management of skin and soft tissue infections in this population unique and challenging.

摘要

养老院获得性皮肤和软组织感染很常见,估计患病率约为5%。此类感染可能是导致严重发病的原因。引起老年人原发性皮肤和软组织感染的病原体种类多样,包括细菌、病毒和真菌感染,以及疥疮或虱子感染。在老年人中,这些感染或感染可能表现为非典型的体征和症状,因此需要高度怀疑。这些皮肤和软组织感染可能会使潜在的慢性皮肤病(如压疮溃疡)复杂化,进一步改变其临床表现。皮肤感染和感染的治疗基于适当的诊断测试。一旦确诊,采用标准药物治疗通常会有良好的临床结果。本文总结了老年人主要的皮肤和软组织感染以及适当的药物治疗,重点关注长期护理居民的特殊考虑因素以及养老院独特的环境,这种环境会导致耐药菌的出现。这些因素使得该人群皮肤和软组织感染的管理具有独特性和挑战性。

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Age changes in glomerular filtration rate, effective renal plasma flow, and tubular excretory capacity in adult males.成年男性肾小球滤过率、有效肾血浆流量和肾小管排泄能力的年龄变化。
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