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[结节病的迟发性并发症——脑积水]

[Hydrocephalus as a late complication of sarcoidosis].

作者信息

Bielska J, Bazowski P, Broda R

出版信息

Neurol Neurochir Pol. 1977;11(3):379-81.

PMID:882216
Abstract

A case of hydrocephalus is described which developed as a late complication of sarcoidosis. In a female patient aged 37 years manifestations of sarcoidosis in the form of Löfgren's syndrome developed 13 years earlier and the diagnosis was confirmed with histological examination of lymph node and bronchial mucosa. After corticoid treatment all manifestations disappeared. In 1975 symptoms of increasing hydrocephalus appeared with violent headaches, visual and hearing disturbances, transient disturbances of consciousness, nausea, vomiting and transient loss of vision with gradually decreasing visual acuity. On the fundus papilloedema was present and angiography and pneumoencephalography demonstrated significant hydrocephalus without shifting of cerebral structures, and without pathological circulation. Surgical treatment (ventriculoatrial shunt) and following corticoid therapy permitted to abolish all symptoms and obtain normalization of eye and improvement of visual acuity.

摘要

本文描述了一例作为结节病晚期并发症而发生的脑积水病例。一名37岁女性患者,13年前出现了以 Löfgren 综合征形式表现的结节病症状,通过淋巴结和支气管黏膜的组织学检查确诊。经皮质激素治疗后,所有症状均消失。1975年,出现了脑积水加重的症状,伴有剧烈头痛、视觉和听觉障碍、短暂意识障碍、恶心、呕吐以及视力逐渐下降并伴有短暂失明。眼底检查发现视乳头水肿,血管造影和气脑造影显示有明显脑积水,但脑结构无移位,也无异常循环。手术治疗(脑室心房分流术)及随后的皮质激素治疗使所有症状消失,眼部情况恢复正常,视力得到改善。

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