Tai T, Akita Y, Kinoshita K, Koyama K, Takahashi K, Watanabe K
Central Research Laboratory Kotaro Pharmaceutical Co. Ltd., Osaka, Japan.
Planta Med. 1995 Dec;61(6):527-30. doi: 10.1055/s-2006-959363.
The triterpenes isolated from P. cocos and their derivatives were examined for anti-emetic activity. Some of these triterpenes inhibited emetic action induced by oral administration of copper sulfate pentahydrate to leopard frog. The triterpenes having an exomethylene group at C-24 showed anti-emetic activity to frogs.
