Rossmann S N, Cernoch P L, Davis J R
Methodist Hospital, Houston, Texas, USA.
Clin Infect Dis. 1996 Jan;22(1):73-80. doi: 10.1093/clinids/22.1.73.
The dematiaceous fungi appear to be an increasing cause of human disease. At The Methodist Hospital, in Houston, Texas, five cases of serious disease caused by these fungi occurred between 1987 and 1992. Cerebral abscesses with Xylohypha bantiana followed treatment for lymphoma. An infection of the lower extremity with Exophiala jeanselmei var. castellanii followed cardiac surgery. Peritoneal growth of Alternaria tenuissima was a complication of peritoneal dialysis. Cerebral abscesses with Dactylaria gallopava occurred in a liver transplantation patient. A traumatic ankle wound contaminated with dirt led to an infection with Phialophora repens. All patients except the last were immunocompromised at the time of the infection; diabetics and patients on steroids may be at particular risk.
暗色真菌似乎越来越多地成为人类疾病的病因。在得克萨斯州休斯敦的卫理公会医院，1987年至1992年间发生了5例由这些真菌引起的严重疾病。淋巴瘤治疗后发生了班替木丝霉所致的脑脓肿。卡氏甄氏外瓶霉变种感染下肢发生在心脏手术后。细极链格孢在腹膜的生长是腹膜透析的并发症。肝移植患者发生了疾驰弯孢所致的脑脓肿。被污垢污染的外伤性脚踝伤口导致了裴氏瓶霉感染。除最后一名患者外，所有患者在感染时均免疫功能低下；糖尿病患者和使用类固醇的患者可能尤其危险。
