Arnman R, Iwarson S, Olsson R
Scand J Gastroenterol. 1977;12(4):387-9. doi: 10.3109/00365527709181677.
The first plasma Factor II-VII-X value after admission to the hospital was higher than 90% in 29% of 38 common duct stone patients, in 9% of 33 patients with bile duct obstruction due to pancreatic carcinoma, and in 3 of 5 patients with cholestatic drug reaction. In contrast, the admission value was above 90% in only one of 89 patients with acute hepatitis and in none of 8 patients with a hepatocellular drug reaction. Therefore, a high plasma Factor II-VII-X activity in a patient with liver or biliary tract disease seems to be a rellained by an increased protein synthesis in the liver.
38例胆总管结石患者中，29%在入院后首次测得的血浆凝血因子II-VII-X值高于90%；33例胰腺癌所致胆管梗阻患者中，9%高于90%；5例胆汁淤积性药物反应患者中，有3例高于90%。相比之下，89例急性肝炎患者中只有1例入院时该值高于90%，8例肝细胞性药物反应患者中无一例高于90%。因此，肝或胆道疾病患者血浆凝血因子II-VII-X活性升高似乎是肝脏蛋白质合成增加所致。
